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How many minutes after administering an oral opiate should you see a peak effect?

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60 minutes

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How many minutes after administering an intravenous opiate should you see a peak effect?

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15 minutes

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For patients with severe cancer related pain, 8/10 or greater, with no response after 15 minutes of intravenous opiate therapy by how many percent can you increase the dose?

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50-100%

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What oral anticholinergics can be used for bowel obstruction?

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Hyoscyamine, scopolamine, glycopyrolate

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What atypical antipsychotic can be used for the treatment of chemotherapy associated nausea ?

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olanzapine

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What is the potency ratio between intravenous and oral morphine?

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3-1

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What antipsychotic can be considered to help with weight gain and cancer related cachexia?

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olanzapine

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What is the molecular target of ondansetron?

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5HT3

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What is the potency ratio between intravenous and oral hydromorphone?

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5-1

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Which opiate is not recommended for cancer related pain?

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Meperidine, because of central nervous system toxicity metabolite

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What is emetogenic potential of acalbrutinib?

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Low risk

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What is the molecular target of apripetant?

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NK1

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What cardiac complication can occur as a side effect of Ondansetron ?

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QT prolongation

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